Strain differences in faecal tryptic activity of germ-free and conventional rats.
نویسندگان
چکیده
Regardless of diet (semi-synthetic or lab chow) or strain (AGUS or SD), germ-free rats have tryptic activity in their faeces, whereas conventional rats never do. The activity in faeces from germ-free AGUS rats was significantly higher than from SD rats.
منابع مشابه
Fat absorption in germ-free and conventional rats artificially deprived of bile secretion.
Bile duct ligation was performed in germ-free and conventional rats in order to study the effects of bile deprivation on the absorption of dietary lipids and the excretion of faecal lipids in the presence or the absence of gastrointestinal flora. The main consequence of bile duct ligation in conventional rats was decrease of about 50% in the apparent absorption of dietary lipids (peanut oil). I...
متن کاملDifferences between germ-free and conventional rats in liver microsomal metabolism of steroids.
The metabolism of some steroids has been investigated in liver microsomal preparations from male germ-free and conventional rats. Hydroxylation of 4-[4-14C]androstene3,17-dione in positions 60 and 16~~ is about 2 and 1.5 times more efficient in germ-free than in conventional rats. The same is true for 6/3and Zol-hydroxylation of 4-[4J4C]pregnene-3,20-dione (about 1.6 and 1.2 times larger, respe...
متن کاملDifferences between Germ-free and Conventional Rats in Liver Microsomal Metabolism of Steroids*
The metabolism of some steroids has been investigated in liver microsomal preparations from male germ-free and conventional rats. Hydroxylation of 4-[4-14C]androstene3,17-dione in positions 60 and 16~~ is about 2 and 1.5 times more efficient in germ-free than in conventional rats. The same is true for 6/3and Zol-hydroxylation of 4-[4J4C]pregnene-3,20-dione (about 1.6 and 1.2 times larger, respe...
متن کاملInfluence of the diet on the turnover of bile acids in germ-free and conventional rats.
I , [z4-14C]cholic acid was given to conventional and germ-free rats and the faecal isotope excretion studied for 8 days. The turnover, pool size and daily excretion of cholic acid and its rnctabolites were calculated for rats on three different diets, i.e. a commercial type diet (pellets), a semi-synthetic diet without (D7) and with 20% cellulose (D7+cellulose). The transit time of theintestin...
متن کاملEffect of CholesterolMetabolitesand PromotingEffect of Lithocholic Acid in Colon Carcinogenesisin Germ-freeand ConventionalF344 Rats1
deoxycholic acid and lithocholic acid, and cholesterol metab olites (10, 28, 26). Patients with colon cancer or nonhereditary adenomatous polyps excrete high levels of fecal secondary bile acids and cholesterol metabolites compared to healthy controls (12, 29). Such a relationship is further supported by experimental studies in animal models (3, 20—22,24). Recently, we have tested both primar...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Laboratory animals
دوره 20 1 شماره
صفحات -
تاریخ انتشار 1986